Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.090 | Biomarker | disease | BEFREE | These results suggest that geniposide attenuates epilepsy in mice through the PI3K/Akt/GSK-3β signaling pathway. | 29399113 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | The role of PI3K/AKT/mTOR signalling pathway has been widely deciphered in pathogenesis of epilepsy. | 31563029 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | The present findings indicate that miRNA‑155 contributes to the occurrence of epilepsy through the PI3K/Akt/mTOR signaling pathway. | 29901097 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | The current study defines the potential role of Trem2 in inhibiting the development of epilepsy, indicating that Trem2 up-regulation alleviates hippocampal neuronal injury and oxidative stress, and inhibits neuronal apoptosis in epilepsy by activating the PI3K/Akt pathway. | 30684126 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | The aim of the present study was to explore the effects of CB2R activation on phosphoinositide 3-kinase (PI3K) 110α-protein kinase B (AKT) signaling in an astrocyte model of epilepsy. | 30542433 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | Selective inhibition of mTORC1/2 or PI3K/mTORC1/2 signaling does not prevent or modify epilepsy in the intrahippocampal kainate mouse model. | 31654704 | 2020 | ||||
|
0.090 | Biomarker | disease | BEFREE | In this study, we explore the ability of long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) to influence the autophagy and apoptosis of hippocampal neurons in epilepsy and the underlying mechanism involving the PI3K/Akt signaling pathway. | 29858824 | 2018 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Date showed that osthole may be useful in the treatment of epilepsy and other neurodegenerative diseases that are characterized by over expression of PI3K/Akt/mTOR. | 30922159 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | PI3K-AKT pathway polymerase chain reaction (PCR) array analysis of epilepsy induced by type II focal cortical dysplasia. | 26345935 | 2015 |